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VOLUME 1.
ISSUE 1. JANUARY-MARCH 2023

ORIGINAL RESEARCH

Anatomic Characteristics of the Apex of the Tooth Root in Georgian Population Using Scanning Electron Microscopy (SEM)

Marina Mamaladze, Lia Sanodze, Manana Ustiashvili, Otar Vadachkoria, Nikoloz Jalabadze

ORIGINAL RESEARCH

Evaluation of Antioxidant and Cytotoxic Activity of Plants Allium Ponticum and Allium Saxatile, Growing in Georgia

Giorgi Jgerenaia, Olivier Bonnet, Carla Hamann, Tsiala Gviniashvili, Michel Frédérich, Nathalie Augé, Lasha Mskhiladze

ORIGINAL RESEARCH

The High-Grade Oxidative Profile (OXpr), Aortic Stiffness Parameters, and Hemogram-Derived Indices (HDI) as Predictors of Long-Term Major Adverse Cardiovascular Events (MACEs) Following Percutaneous Coronary Intervention (PCI) in Patients with Non-ST-Elevation Acute Coronary Syndrome (NSTE-ACS) and Chronic Coronary Syndrome (CCS)

Zaza Lominadze, Kakhaber Chelidze, Levan Chelidze, Ekaterine Lominadze

CLINICAL CASE

Surgical Intervention vs Observation in the Management of Gallbladder Polyps: A Case Series

Gia Tomadze, Avtandil Megreladze, Laya Chadalawada, Rohit Parab

ORIGINAL RESEARCH

Rheological Changes During the Atrial Fibrillation

Maia Gotsadze, Tamar Kandashvili, Nana Momtselidze, Maka Mantskava

ORIGINAL RESEARCH

Infrared Visualization of the Prostate Cancer

Sopio Abazadze, Alexandre Khuskivadze, Besarion Partsvania, Tamaz Sulamberidze, Davit Kochiashvili, Omar Khardzeishvili

ORIGINAL RESEARCH

Peculiarities of Angiogenesis of the Uterine Body Leiomyomas in Women of Reproductive Age

Mindia Iobashvili, Marina Pailodze, Irma Jikia, Anzor Gogiberidze, Nikoloz Vachadze, Magda Tortladze, Evgeni Asatiani

ORIGINAL RESEARCH

Antiplatelet Therapy for Secondary Prevention After Myocardial Infarction in Antiplatelet-Naive High Cardiovascular Risk Patients with Non-Obstructive Coronary Artery Disease

Ioseb Sikharulidze, Kakhaber Chelidze, Merab Mamatsashvili, Levan Chelidze, Tamar Kajaia, Irma Bakhlishvili

ORIGINAL RESEARCH

Improvement of Targeted Therapy by E. coli Phage-lysate Vaccination: Tumor Microenvironment Modulation and Magnetic Nanoparticle Delivery Enhancement in Tumor Tissue

Ketevan Ghambashidze, Ramaz Chikhladze, Tamar Saladze, Fridon Shubitidze

ORIGINAL RESEARCH

Protective Effect of Herniarin on the Ionizing Radiation-Induced Alterations of Erythrocyte Membrane Proteins

Sophio Kalmakhelidze, Eka Shekiladze, Davit Topuria, Tamar Sanikidze

ORIGINAL RESEARCH

Peri-Implant Sulcular Fluid (PISF) Nitric Oxide (NO) as an Early Marker of Inflammation

Emir Bayandurov, Zurab Orjonikidze, Tamar Sanikidze

ORIGINAL RESEARCH

Comparison of Inflammatory and Oxidative Stress Markers Among Patients with Non-Obstructive vs. Obstructive Coronary Artery Disease

Ioseb Sikharulidze, Kakhaber Chelidze, Levan Chelidze, Tamar Kajaia, Irma Bakhlishvili

ORIGINAL RESEARCH

Autoimmunity and Clinical Markers in Chronic Spontaneous Urticaria: A Retrospective Cohort Study

Bidzina Kulumbegov, Maia Gotua, Tinatin Chikovani

ORIGINAL RESEARCH

Genetic Heterogeneity of Iduronate-2-Sulfatase in Children Diagnosed with Mucopolysaccharidosis Type II in Azerbaijan

Alizada Sevda Aydin, Aliyeva Kamila Ali Agha, Musayev Shirkhan Aftandil, Rasulov Elkhan Mammad Rasul

ISSUE 2. APRIL-JUNE 2023

ORIGINAL RESEARCH

Comparative safety study of the phenolic constituents of smokebush (Cotinus coggygria) leaves

Tamar Shavadze, Natia Nizharadze, Marina Mamaladze, Ketevan Shalashvili, Marine Sulakvelidze, Zhana Novikova, Karen Mulkijanyan, Eter Kemertelidze

REVIEW ARTICLE

The Key Issues Related to Features and Perspectives of Antioxidants in Asthma and Allergy Pharmacotherapy

Nana Gorgaslidze, Ia Panstulaia, Marina Giorgobiani, Nodar Sulashvili

ORIGINAL RESEARCH

The Possible Relationship Between ABO and Rhesus System Phenotypes and SARS-CoV-2 Infection

Marina Nagervadze, Leila Akhvlediani, Teona Phutkaradze, Mamuka Sikharulidze, Shorena Gabaidze, Sophiko Tskvitinidze, Salome Abuladze, Rusudan Khukhunaishvili, Marina Koridze, Ketevan Dolidze  

The Humoral Immunity Features of COVID-19 in the West Georgia Population

Nana Shavlakadze, Dali Kobuladze

REVIEW ARTICLE

Understanding the Complexities of Melanoma Immunobiology and a Reviewof Immunotherapeutic Checkpoint Inhibitors

Tina Kituashvili, Tamari Urushadze

ORIGINAL RESEARCH

Frequent Cases of Spondylarthritis and Hereditary Propensity (HLA-B27) in the Same Family Name Relatives from the Keda Region of Ajara, Georgia

Neriman Tsintsadze, Nazibrola Tsivadze, Ia Kakhidze, Lia Saginadze, Rusudan Vadatchkoria

ORIGINAL RESEARCH

Analysis of the Diagnostic Markers in Patients with Post-COVID-19 disorders

Revaz Sepiashvili, Manana Chikhladze, Sopio Gamkrelidze,Darejan Khachapuridze, Nino Jojua, Dali Shovnadze

ORIGINAL RESEARCH

Microstructural Features of Primula woronowii Losinsk., Primula macrocalyx Bunge. and Primula saguramica Gavr. from Georgian Flora

Nino Sukhishvili, Ketevan Mchedlidze, Karen Mulkijanyan, Lasha Mskhiladze

ORIGINAL RESEARCH

Morphological Changes of the Portal Triad During Experimental Cholangitis

Ketevan Jandieri, Tamar Turmanidze, Liana Kikalishvili, Leila Jandieri

ORIGINAL RESEARCH

Infrared Visualization of Prostate Cancer Tissues with Various Gleason Scores

Sopio Abazadze, â€‹Alexandre Khuskivadze, Besarion Partsvania, Tamaz Sulamberidze, Davit Kochiashvili, Omar Khardzeishvili

ORIGINAL RESEARCH

Predictive Biomarkers of Thyroid Dysfunctions Associated with the Treatment of Non-Small Cell Lung Cancer and Cervical Cancer with Immune Checkpoint Inhibitors

Ketevan Lomidze, ​Nino Kikodze, Marine Gordeladze, Tinatin Chikovani, Nino Charkviani

ORIGINAL RESEARCH

Prevalence of Cognitive Disorders and Depression in the Adjara Region, Georgia, Before and After the COVID-19 Pandemic

Shorena Vashadze, â€‹Mariam Kekenadze

ORIGINAL RESEARCH

Novel Bronchoscopic Management of Bleeding from The Respiratory Tract

Teona Mskhaladze, David Tchkonia, Kakha Vacharadze, Gia Lursmanashvili, Natia Adamia, Mikolay Chkonia

ORIGINAL RESEARCH

High risk of cardiovascular disease in patients with chronic plaque psoriasis

Kakhaber Chelidze, Irma Mamatsashvili, Medea Jgharkava, Maia Matoshvili, Khatuna Khijakadze, Eter Tsetskhladze

ORIGINAL RESEARCH

Comparison of Long-term Preventive Effects of Dual Antiplatelet Therapy vs. Monotherapy in High Cardiovascular Risk Patients After Myocardial Infarction with Nonobstructive Coronary Arteries (MINOCA)

Ioseb Sikharulidze, Kakhaber Chelidze, Levan Chelidze, Tamar Kajaia, Irma Bakhlishvili

ORIGINAL RESEARCH

Epstein–Barr Virus Infection in Children Following Acute SARS-CoV-2 Infection

Irine Korinteli, Irma Korinteli, Leli Shanidze, Mzia Khalvashi, Eliso Turkadze

CLINICAL CASE

Periprocedural Off-label Use of Rivaroxaban in Patient with Atrial Fibrillation and a Persistent Left Atrial Appendage Thrombus Despite Standard Anticoagulation Therapy: A Case Report

Archil Chukhrukidze, Zviad Kereselidze

ORIGINAL RESEARCH

Neurocognitive Characteristics of Major Depressive Disorder Measured by Degraded Continuous Performance Test

Ekaterine Berdzenishvili, Maia Roinishvili, Mariam Okruashvili, Eter Machavariani, Eka Chkonia

ISSUE 3. JULY-SEPTEMBER 2023

ORIGINAL RESEARCH

Heterogeneity in INF-γ Levels Among Children with Different Types of Epilepsy

Tatia Gakharia, Sophia Bakhtadze, Nana Khachapuridze, Nana Kapanadze

CLINICAL CASE

The Diagnostic Value of MRI in Children with Acute Hematogenous Osteomyelitis

Grigol Nemsadze, Otar Urushadze, Giorgi Apkhazava, Vladimer Talakvadze, Luka Nemsadze

ORIGINAL RESEARCH

Clinical Features of the Development and Treatment of Carious and Non-carious Lesions in the Cervical Area of Human Teeth

Ekaterine Zarkua, Marina Mamaladze, Lali Khustishvili

ORIGINAL RESEARCH

Diagnostic Capabilities of Ultra-low-dose Computed Tomography with a Dose Equivalent to Chest X-ray Radiography

Giorgi Apkhazava, Grigol Nemsadze, Ivane Chkhaidze, Otar Urushadze

ORIGINAL RESEARCH

Comparative Analysis of Pilonidal Abscess Drainage

Erekle Gratiashvili, Lali Akhmeteli, Teimuraz Ivanishvili, Salome Kobadze, Nodar Giorgadze

ORIGINAL RESEARCH

Diagnosis and Treatment Options of Endo-Perio Lesions

Nazim A. Panahov, Vusalya M. Bayramova, Fuad Y. Mamedov, Ilgar T. Gajar

ISSUE 4. OCTOBER-DECEMBER 2023

REVIEW ARTICLE

Healthy Nutrition Can Impact Women's Fertility – Myth or Reality?

Tamar Khurtsilava

CLINICAL CASE

Dextrocardia with Situs Inversus Totalis: Off-Pump Coronary Bypass Surgery in a 63-Year-Old Male Patient

Lasha Basiladze, Simon Matikashvili, Levan Chelidze, Lasha Tabagari, Irakli Shurgaia

CLINICAL CASE

Early Dermatological Manifestations of Lyme Disease

Nestan Merkviladze, Tinatin Gaidamashvili, Paata Tushurashvili, Eka Ekaladze

ORIGINAL RESEARCH

Interrelationship of Hepatic Veins with Separate Components of Portal Triad

Revaz Otarashvili, Ketevan Jandieri, Tamar Turmanidze, Liana Kikalishvili, Leila Jandieri, Ilia Chanukvadze

REVIEW ARTICLE

The Experimental Models of Acute Pancreatitis

Levan Benashvili

ORIGINAL RESEARCH

Chemical Composition and Biological Activity of Aerial Parts of Thymus collinus Bieb. Growing in Georgia

Teona Korkotadze, Dali Berashvili, Sopio Gokadze, Malkhaz Jokhadze, Malkhaz Getia, Ketevan Mchedlidze, Jean Legault,
Vakhtang Mshvildadze

REVIEW ARTICLE

Right Ventricular Global Longitudinal Strain and Its Role in the Prediction of Chemotherapy-Induced Cardiovascular Toxicity

Nana Gorgiladze, Zurab Pagava, Tamar Gaprindashvili, Mikheil Shavdia

ORIGINAL RESEARCH

Technology and Composition of Saperavi-Based Cosmetic Emulgel

Tamar Kirvalidze, Lasha Bakuridze, Dali Berashvili, Gulnara Mikaia, Ia Tsurtsumia, Tamaz Murtazashvili, Aliosha Bakuridze

REVIEW ARTICLE

Parental Nutritional Awareness for Enhancement of Child Nutrition and Healthy Lifestyle: A Literature Review

Rusudan Gvamichava, Levan Baramidze, Ihab Tewfik

REVIEW ARTICLE

Review of Dietary Supplement Regulation

Lali Dateshidze, Dali Berashvili, Nugzar Todua

REVIEW ARTICLE

Cell Engineering Potential in Regenerative Endodontics

Tamta Jikia, Nino Chipashvili

ORIGINAL RESEARCH

Morphological Changes Around the Portal Complex and Hepatic Vein During Experimental Cholangitis

Revaz Otarashvili, Ketevan Jandieri,Tamar Turmanidze, Liana Kikalishvili, Leila Jandieri, Ilia Chanukvadze

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